Claire Pouplard Selected Research

Platelet Factor 4

10/2022	The deglycosylated form of 1E12 inhibits platelet activation and prothrombotic effects induced by VITT antibodies.
1/2022	Genome-wide association study of platelet factor 4/heparin antibodies in heparin-induced thrombocytopenia.
1/2022	ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia.
3/2021	Characterization of New Monoclonal PF4-Specific Antibodies as Useful Tools for Studies on Typical and Autoimmune Heparin-Induced Thrombocytopenia.
4/2020	Detection of Platelet-Activating Antibodies Associated with Heparin-Induced Thrombocytopenia.
1/2019	Cleavage of anti-PF4/heparin IgG by a bacterial protease and potential benefit in heparin-induced thrombocytopenia.
12/2017	Beneficial effect of exogenous platelet factor 4 for detecting pathogenic heparin-induced thrombocytopenia antibodies.
4/2015	A genome-wide association study of heparin-induced thrombocytopenia using an electronic medical record.
6/2013	Incidence of antibodies to protamine sulfate/heparin complexes incardiac surgery patients and impact on platelet activation and clinical outcome.
8/2012	Polymorphisms of protein tyrosine phosphatase CD148 influence FcγRIIA-dependent platelet activation and the risk of heparin-induced thrombocytopenia.

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Claire Pouplard Research Topics

Disease

36	Thrombocytopenia (Thrombopenia) 10/2022 - 05/2003
6	Thrombosis (Thrombus) 10/2022 - 04/2006
5	Hemorrhage 08/2021 - 06/2003
4	Hemophilia A (Haemophilia) 12/2020 - 10/2009
2	COVID-19 10/2022 - 10/2021
2	Thrombotic Microangiopathies 01/2021 - 01/2019
2	Infections 01/2021 - 01/2019
2	Thrombophilia 01/2019 - 10/2016
2	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) 12/2007 - 05/2003
1	Chronic Kidney Failure (Chronic Renal Failure) 01/2022
1	Drug-Related Side Effects and Adverse Reactions 01/2022
1	Atypical Hemolytic Uremic Syndrome 01/2022
1	Neuralgia (Stump Neuralgia) 08/2021
1	Hemolytic-Uremic Syndrome 01/2021
1	Wounds and Injuries (Trauma) 01/2021
1	Heart Failure 07/2019
1	Malignant Hypertension 01/2019
1	Sickle Cell Anemia (Hemoglobin S Disease) 01/2019
1	Autoimmune Diseases (Autoimmune Disease) 01/2019
1	Neoplasms (Cancer) 01/2019
1	Hemophilia B (Haemophilia B) 01/2019
1	Glucosephosphate Dehydrogenase Deficiency 01/2019
1	Thromboembolism 11/2009
1	Renal Insufficiency (Renal Failure) 04/2006
1	Disseminated Intravascular Coagulation 06/2003
1	Venous Thrombosis (Deep-Vein Thrombosis) 05/2003
1	Habitual Abortion (Recurrent Miscarriage) 05/2003

Drug/Important Bio-Agent (IBA)

31	Heparin (Liquaemin)FDA LinkGeneric 01/2022 - 06/2003
20	AntibodiesIBA 10/2022 - 05/2003
16	Platelet Factor 4IBA 10/2022 - 11/2004
15	Immunoglobulin G (IgG)IBA 10/2022 - 11/2004
5	Serotonin (5 Hydroxytryptamine)IBA 10/2021 - 12/2007
5	Biological ProductsIBA 01/2021 - 06/2003
3	VaccinesIBA 10/2022 - 01/2021
3	EnzymesIBA 10/2021 - 12/2007
3	Factor VIII (Coagulation Factor VIII)IBA 08/2020 - 10/2009
2	AnticoagulantsIBA 01/2022 - 09/2008
2	Intravenous Immunoglobulins (IVIG)FDA Link 12/2021 - 12/2021
2	Shiga Toxin (Shigella Toxin)IBA 01/2021 - 01/2019
2	lepirudin (Refludan)FDA Link 09/2008 - 04/2006
2	danaparoid (Orgaran)FDA Link 09/2008 - 04/2006
1	FibrinIBA 10/2022
1	estropipate (Ogen)FDA LinkGeneric 10/2022
1	COVID-19 VaccinesIBA 10/2022
1	Blood Group Antigens (Blood Groups)IBA 01/2022
1	eculizumab FDA Link 01/2022
1	Gabapentin (Neurontin)FDA LinkGeneric 08/2021
1	CollagenIBA 08/2021
1	Epinephrine (Adrenaline)FDA LinkGeneric 08/2021
1	Adenosine Diphosphate (ADP)IBA 08/2021
1	gamma-Aminobutyric Acid (GABA)IBA 08/2021
1	Arachidonic Acid (Vitamin F)IBA 08/2021
1	Hemoglobins (Hemoglobin)IBA 01/2021
1	Thromboplastin (Tissue Factor)IBA 12/2020
1	Monoclonal AntibodiesIBA 12/2020
1	emicizumabIBA 12/2020
1	Pharmaceutical PreparationsIBA 04/2020
1	polyanionsIBA 01/2019
1	Factor IX (Coagulation Factor IX)FDA LinkGeneric 01/2019
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2019
1	Peptide Hydrolases (Proteases)FDA Link 01/2019
1	Protein Isoforms (Isoforms)IBA 10/2016
1	Fc Receptors (Fc Receptor)IBA 04/2015
1	Protamines (Protamine Sulfate)FDA Link 06/2013
1	Protein Tyrosine PhosphatasesIBA 08/2012
1	Interleukin-10 (Interleukin 10)IBA 04/2012
1	argatroban (MPQA)FDA Link 09/2008
1	Thrombin FDA Link 09/2008
1	InterleukinsIBA 12/2007
1	Fc gamma receptor IIAIBA 11/2004
1	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 06/2003
1	Antiphospholipid AntibodiesIBA 05/2003

Therapy/Procedure

5	Therapeutics 12/2020 - 06/2003
2	Transplantation 01/2022 - 01/2019
2	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/2021 - 03/2005
1	Surgical Amputation (Amputations) 11/2009